Eurycoma longifolia, a promising suppressor of RANKL-induced differentiation and activation of osteoclasts: An in vitro mechanistic evaluation

Eurycoma longifolia, a promising suppressor of RANKL-induced differentiation and activation of osteoclasts: An in vitro mechanistic evaluation

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Background: Eurycoma longifolia (E. longifolia) has gained remarkable recognition due to its promising efficacy of stimulating bone formation in androgen-deficient osteoporosis. Numerous in vivo studies have explored the effects of E. longifolia on osteoporosis; however, the in vitro cellular mechan...

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Bibliographic Details
Main Authors: Hussain, Z (Author), Mohamed, IN (Author), Shuid, AN (Author), Thu, HE (Author)
Format: Article
Language:English
Published: 2019
Subjects:
Bone resorption
BONE-RESORPTION
CATHEPSIN-K
CELLS
Eurycoma longifolia
EXPRESSION
KAPPA-B LIGAND
MATRIX-METALLOPROTEINASE-9
Molecular mechanism
Osteoclastogenesis
Osteoclasts
Osteoporosis
OSTEOPOROSIS
QUASSINOIDS
RAW264.7
RECEPTOR ACTIVATOR
Online Access:View Fulltext in Publisher
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008 220223s2019 CNT 000 0 und d
245 1 0 |a Eurycoma longifolia, a promising suppressor of RANKL-induced differentiation and activation of osteoclasts: An in vitro mechanistic evaluation 
260 0 |c 2019 
650 0 4 |a Bone resorption 
650 0 4 |a BONE-RESORPTION 
650 0 4 |a CATHEPSIN-K 
650 0 4 |a CELLS 
650 0 4 |a Eurycoma longifolia 
650 0 4 |a EXPRESSION 
650 0 4 |a KAPPA-B LIGAND 
650 0 4 |a MATRIX-METALLOPROTEINASE-9 
650 0 4 |a Molecular mechanism 
650 0 4 |a Osteoclastogenesis 
650 0 4 |a Osteoclasts 
650 0 4 |a Osteoporosis 
650 0 4 |a OSTEOPOROSIS 
650 0 4 |a QUASSINOIDS 
650 0 4 |a RAW264.7 
650 0 4 |a RECEPTOR ACTIVATOR 
856 |z View Fulltext in Publisher  |u https://doi.org/10.1016/j.jaim.2017.07.014 
520 3 |a Background: Eurycoma longifolia (E. longifolia) has gained remarkable recognition due to its promising efficacy of stimulating bone formation in androgen-deficient osteoporosis. Numerous in vivo studies have explored the effects of E. longifolia on osteoporosis; however, the in vitro cellular mechanism was not discovered yet. 
700 1 0 |a Hussain, Z  |e author 
700 1 0 |a Mohamed, IN  |e author 
700 1 0 |a Shuid, AN  |e author 
700 1 0 |a Thu, HE  |e author 
773 |t JOURNAL OF AYURVEDA AND INTEGRATIVE MEDICINE 

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