Assessing the influence of neglected GC-FID variables on the multiple responses using multivariate optimization for the determination of ethanol and acetonitrile in radiopharmaceuticals

Assessing the influence of neglected GC-FID variables on the multiple responses using multivariate optimization for the determination of ethanol and acetonitrile in radiopharmaceuticals

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Analytical gas chromatography in line with a flame ionization detector (GC-FID) method was developed and validated for direct determination of organic solvents in [F-18]fluoro-ethyl-tyrosine ([F-18]FET), [F-18]fluoromisonidazole ([F-18]FMISO) and [F-18]fluorothymidine ([F-18]FLT). Variables of the s...

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Bibliographic Details
Main Authors: Abdul Razak, HR (Author), Ahmad Saad, FF (Author), Hassan, H (Author), Othman, MF (Author), Zakaria, ZA (Author)
Format: Article
Language:English
Published: 2021
Subjects:
Gas chromatography-flame ionization detection (GC-FID)
Injection temperature
Organic solvent analysis
Quality control
Radiopharmaceutical
RESIDUAL SOLVENTS
Splitless time
Online Access:View Fulltext in Publisher

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