N-Cadherin cleavage during activated hepatic stellate cell apoptosis is inhibited by tissue inhibitor of metalloproteinase-1. [In supplement: 11th International Symposium on the Cells of the Hepatic Sinusoid and their Relation to Other Cells]
Apoptosis of hepatic stellate cells (HSC) has previously been shown to occur during spontaneous resolution of experimental liver fibrosis. TIMP-1 has also been shown to have a key role because of its ability to inhibit apoptosis of HSC via matrix metalloproteinase (MMP) inhibition. This has led to f...
Main Authors: | Murphy, Frank (Author), Waung, Julian (Author), Collins, Jane (Author), Arthur, Michael J.P (Author), Nagase, Hideaki (Author), Mann, Derek (Author), Benyon, R. Christopher (Author), Iredale, John P. (Author) |
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Format: | Article |
Language: | English |
Published: |
2004-01-14.
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Subjects: | |
Online Access: | Get fulltext |
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