Position-dependent repression and promotion of DQB1 intron 3 splicing by GGGG motifs
Alternative splicing of HLA-DQB1 exon 4 is allele-dependent and results in variable expression of soluble DQbeta. We have recently shown that differential inclusion of this exon in mature transcripts is largely due to intron 3 variants in the branch point sequence (BPS) and polypyrimidine tract. To...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
2006-02.
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| Subjects: | |
| Online Access: | Get fulltext |