BRCA1 and BRCA2 genetic testing - pitfalls and recommendations for managing variants of uncertain clinical significance

Background Increasing use of BRCA1/2 testing for tailoring cancer treatment and extension of testing to tumour tissue for somatic mutation is moving BRCA1/2 mutation screening from a primarily prevention arena delivered by specialist genetic services into mainstream oncology practice. A considerabl...

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Bibliographic Details
Main Authors: Eccles, D. (Author), Mitchell, G. (Author), Monteiro, A.N.A (Author), Schmutzler, R. (Author), Couch, F.J (Author), Spurdle, A.B (Author), Gómez-García, E.B (Author)
Format: Article
Language:English
Published: 2015-10-10.
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