Variant B cell receptor isotype functions differ in hairy cell leukemia with mutated BRAF and IGHV genes
A functional B-cell receptor (BCR) is critical for survival of normal B-cells, but whether it plays a comparable role in B-cell malignancy is as yet not fully delineated. Typical Hairy Cell Leukemia (HCL) is a rare B-cell tumor, and unique in expressing multiple surface immunoglobulin (sIg) isotypes...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
2014-01-30.
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| Subjects: | |
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