Identification of BDNF sensitive electrophysiological markers of synaptic activity and their structural correlates in healthy subjects using a genetic approach utilizing the functional BDNF Val66Met polymorphism

Identification of BDNF sensitive electrophysiological markers of synaptic activity and their structural correlates in healthy subjects using a genetic approach utilizing the functional BDNF Val66Met polymorphism

Increasing evidence suggests that synaptic dysfunction is a core pathophysiological hallmark of neurodegenerative disorders. Brain-derived neurotropic factor (BDNF) is key synaptogenic molecule and targeting synaptic repair through modulation of BDNF signalling has been suggested as a potential drug...

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Main Authors: Fox, Michael A. (Author), Soltész, Fruzsina (Author), Suckling, John (Author), Lawrence, Phil (Author), Tait, Roger (Author), Ooi, Cinly (Author), Bentley, Graham (Author), Dodds, Chris M. (Author), Miller, Sam R. (Author), Wille, David R. (Author), Byrne, Misha (Author), McHugh, Simon M. (Author), Bellgrove, Mark A. (Author), Croft, Rodney J. (Author), Lu, Bai (Author), Bullmore, Edward T. (Author), Nathan, Pradeep J. (Author)
Format: Article
Language:English
Published: 2014-04-23.
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