Screening ion-channel ligand interactions with passive pumping in a microfluidic bilayer lipid membrane (BLM) chip
We describe a scalable artificial bilayer lipid membrane (BLM) platform for rapid electrophysiological screening of ion channels and transporters. A passive pumping method is used to flow microliter volumes of ligand solution across a suspended bilayer within a microfluidic chip. Bilayers are stable...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
2015-01-09.
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Subjects: | |
Online Access: | Get fulltext |