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|a Systemic lupus erythematosus (SLE) can manifest in the lower limb with joint and muscle pains and in severe cases, disorganisation of the joints and tendon rupture. In the foot and lower limb, Raynaud's phenomenon and other circulatory problems have been reported and may be associated with loss of sensation or altered pain perception. Associated with impaired peripheral neurovascular function are changes in tissue viability leading to either callus formation or thinning of the skin and ulceration. Many medications used to manage SLE can impact on the person's resistance to infections and consequently fungal, bacterial or viral infections can spread rapidly and persist. Although there is some evidence for this range of problems occurring in the foot, it is not known how prevalent they are, what interaction there is between problems, and how these impact upon a person's health related quality of life (HRQoL). Thus, the main aim of this study is to determine the self-reported foot and lower limb problems experienced by people with SLE. A secondary aim is to explore the impact that the identified foot and lower complications may have upon patients with SLE. It is anticipated that this research will highlight areas of potential health care need and thus can be used to inform recommendations about foot health care for this patient group and the focus of future research.
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