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00971 am a22001813u 4500 |
| 001 |
362483 |
| 042 |
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|a dc
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| 100 |
1 |
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|a Chavda, Jai K.
|e author
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| 700 |
1 |
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|a Procopiou, Panayiotis A.
|e author
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1 |
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|a Horton, Peter N.
|e author
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1 |
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|a Coles, Simon J.
|e author
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|a Porter, Michael J.
|e author
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| 245 |
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|a Synthetic studies towards the core structure of nakadomarin A by a thioamide-based strategy
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| 260 |
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|c 2014-01.
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| 856 |
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|z Get fulltext
|u https://eprints.soton.ac.uk/362483/1/pdf
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| 520 |
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|a The tricyclic BCD substructure of the marine natural product nakadomarin A has been synthesised. The strategy utilised a key carbon-carbon bond-forming reaction between a furan and an N-acyliminium ion derived from a secondary thiolactam. In addition, a novel three-component coupling reaction between a thioamide, an allylic bromide and an isocyanate, leading to the establishment of two new stereogenic centres, is reported.
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| 540 |
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|a other
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| 655 |
7 |
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|a Article
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