ß3 integrin modulates transforming growth factor beta induced (TGFBI) function and paclitaxel response in ovarian cancer cells.

The extracellular matrix (ECM) has a key role in facilitating the progression of ovarian cancer and we have shown recently that the secreted ECM protein TGFBI modulates the response of ovarian cancer to paclitaxel-induced cell death.

Bibliographic Details
Main Authors: Tumbarello, David A. (Author), Temple, Jillian (Author), Brenton, James D. (Author)
Format: Article
Language:English
Published: 2012-05-28.
Subjects:
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