Choline-releasing glycerophosphodiesterase EDI3 links the tumor metabolome to signaling network activities.
Recently, EDI3 was identified as a key factor for choline metabolism that controls tumor cell migration and is associated with metastasis in endometrial carcinomas. EDI3 cleaves glycerophosphocholine (GPC) to form choline and glycerol-3-phosphate (G3P). Choline is then further metabolized to phospha...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
2012-12-15.
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| Subjects: | |
| Online Access: | Get fulltext |