A DNA based five-state switch with programmed reversibility
A programmable switch based on a DNA hairpin loop is functionalised with a rigid or flexible porphyrin or FAM and TAMRA FRET pair, which provides insight into the restructuring of the hairpin as well as porphyrin-porphyrin coupling. The switch contains five discrete states which can be accessed inde...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
2012-09-24.
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| Subjects: | |
| Online Access: | Get fulltext |
| Summary: | A programmable switch based on a DNA hairpin loop is functionalised with a rigid or flexible porphyrin or FAM and TAMRA FRET pair, which provides insight into the restructuring of the hairpin as well as porphyrin-porphyrin coupling. The switch contains five discrete states which can be accessed independently and followed by real-time spectroscopy, opening the way to a quinary computing code. |
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