Paradoxical fate and biological action of peroxynitrite on human platelets

Paradoxical fate and biological action of peroxynitrite on human platelets

Peroxynitrite (ONOO-), which is formed from the reaction of nitric oxide (NO) and superoxide (O2-), has been suggested to be responsible for some of the cytotoxic effects of these molecules. When protonated, ONOO- gives rise to hydroxyl (OH.) and nitrogen dioxide (NO2) radicals, which are capable of...

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Main Authors: Moro, María Ángeles (Author), Darley-Usmar, Victor M. (Author), Goodwin, David A. (Author), Read, Nicholas G. (Author), Zamora-Pino, Rubén (Author), Feelisch, Martin (Author), Radomski, Marek W. (Author), Moncada, Salvador (Author)
Format: Article
Language:English
Published: 1994-07-05.
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