Nramp1 functionality increases inducible nitric oxide synthase transcription via stimulation of IFN regulatory factor 1 expression
Natural-resistance associated macrophage protein 1 (Nramp1) encodes a transmembrane phagolysosomal protein exerting resistance toward infections with intracellular pathogens by a mechanism not fully elucidated so far. We used the murine macrophagecell line RAW264.7, stably transfected with functiona...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
2003-08-15.
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Subjects: | |
Online Access: | Get fulltext |