Evaluation of VEGF-mediated signaling in primary human cells reveals a paracrine action for VEGF in osteoblast-mediated crosstalk to endothelial cells

Communication between endothelial and bone cells is crucial for controlling vascular supply during bone growth, remodeling, and repair but the molecular mechanisms coordinating this intercellular crosstalk remain ill-defined. We have used primary human and rat long bone-derived osteoblast-like cells...

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Bibliographic Details
Main Authors: Clarkin, Claire E. (Author), Emery, Roger J. (Author), Pitsillides, Andrew A. (Author), Wheeler-Jones, Caroline P.D (Author)
Format: Article
Language:English
Published: 2008-02.
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