Crystal structure of a bacterial chitinase at 2.3 A resolution

Crystal structure of a bacterial chitinase at 2.3 A resolution

The reaction mechanism seems to be similar to that of lysozyme and most other glycosylhydrolases, i.e. general acid-base catalysis. The role of the amino-terminal domain could not be identified, but it has similarities to the fibronectin III domain. This domain may possibly facilitate the interactio...

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Bibliographic Details
Main Authors: Perrakis, A (Author), Tews, I (Author), Dauter, Z (Author), Oppenheim, A B (Author), Chet, I (Author), Wilson, K S (Author), Vorgias, C E (Author)
Format: Article
Language:English
Published: 1994-12-15.
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Summary:The reaction mechanism seems to be similar to that of lysozyme and most other glycosylhydrolases, i.e. general acid-base catalysis. The role of the amino-terminal domain could not be identified, but it has similarities to the fibronectin III domain. This domain may possibly facilitate the interaction of chitinase A with chitin.

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