Possible inhibitory effects of terbinafine on aripiprazole metabolism: Two case reports

Aripiprazole, an atypical antipsychotic, is a metabolic substrate for cytochrome P450 (CYP)3A4 and 2D6. Terbinafine, an antifungal agent used for onychomycosis, is a CYP2D6 inhibitor and could theoretically reduce the metabolism of aripiprazole. However, there are no published reports describing thi...

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Bibliographic Details
Main Authors: Lindbloom, T.J (Author), McGrane, I.R (Author), Munjal, R.C (Author)
Format: Article
Language:English
Published: Allen Press Inc. 2021
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Online Access:View Fulltext in Publisher