Perphenazine and prochlorperazine decrease glioblastoma U-87 MG cell migration and invasion: Analysis of the ABCB1 and ABCG2 transporters, E-cadherin, α-tubulin and integrins (α3, α5, and β1) levels

Perphenazine and prochlorperazine decrease glioblastoma U-87 MG cell migration and invasion: Analysis of the ABCB1 and ABCG2 transporters, E-cadherin, α-tubulin and integrins (α3, α5, and β1) levels

Glioblastoma multiforme is the most frequent type of malignant brain tumor, and is one of the most lethal and untreatable human tumors with a very poor survival rate. Therefore, novel and effective strategies of treatment are required. Integrins play a crucial role in the regulation of cellular adhe...

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Bibliographic Details
Main Authors: Kabala-Dzik, A. (Author), Otreba, M. (Author), Rzepecka-Stojko, A. (Author), Stojko, J. (Author)
Format: Article
Language:English
Published: Spandidos Publications 2022
Subjects:
ABCB1
ABCG2
and β1)
E-cadherin
integrins (α3
invasion
migration
perphenazine
prochlorperazine
U-87 MG cells
α5
α-tubulin
Online Access:View Fulltext in Publisher

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