The impact of radiation therapy on the TCR Vβ chain repertoire in patients with prostate cancer

The impact of radiation therapy on the TCR Vβ chain repertoire in patients with prostate cancer

Radiation therapy (RT) is an essential component in the therapeutic treatment of patients with localized prostate cancer (LPCa). Besides its local effects, ionizing radiation has been linked to mechanisms leading to systemic immune activation. The present study explored the effect of RT on the T‑cel...

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Bibliographic Details
Main Authors: Adamaki, M. (Author), Batsaki, P. (Author), Baxevanis, C.N (Author), Davanos, N. (Author), Fortis, S.P (Author), Goulielmaki, M. (Author), Gritzapis, A.D (Author), Kogionou, P. (Author), Mosa, E. (Author), Stokidis, S. (Author), Vasilakou, E. (Author), Zambatis, C. (Author), Zoumpourlis, V. (Author)
Format: Article
Language:English
Published: NLM (Medline) 2022
Subjects:
clonotype frequencies
genetics
human
Humans
lymphocyte antigen receptor
male
Male
prostate cancer
prostate tumor
Prostatic Neoplasms
radiation therapy
Receptors, Antigen, T-Cell, alpha-beta
T cell
T‑cell receptor variable β
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