Diagnosis of murine typhus by serology in peninsular Malaysia: A case report where rickettsial illnesses, leptospirosis and dengue co-circulate
Murine typhus is a rarely diagnosed cause of acute febrile illness in Malaysia, and its true disease burden is unknown. We report a case of an acute murine typhus infection in a patient living in a small city in Peninsular Malaysia, presenting with fever, rash, and headache. Unresponsive to the init...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2019
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| Subjects: | |
| Online Access: | View Fulltext in Publisher View in Scopus |
| LEADER | 02381nam a2200541Ia 4500 | ||
|---|---|---|---|
| 001 | 10.3390-tropicalmed4010023 | ||
| 008 | 220121s2019 CNT 000 0 und d | ||
| 020 | |a 24146366 (ISSN) | ||
| 245 | 1 | 0 | |a Diagnosis of murine typhus by serology in peninsular Malaysia: A case report where rickettsial illnesses, leptospirosis and dengue co-circulate |
| 260 | 0 | |b MDPI AG |c 2019 | |
| 650 | 0 | 4 | |a adult |
| 650 | 0 | 4 | |a Article |
| 650 | 0 | 4 | |a case report |
| 650 | 0 | 4 | |a clinical article |
| 650 | 0 | 4 | |a dengue |
| 650 | 0 | 4 | |a Diagnosis |
| 650 | 0 | 4 | |a doxycycline |
| 650 | 0 | 4 | |a fever |
| 650 | 0 | 4 | |a headache |
| 650 | 0 | 4 | |a human |
| 650 | 0 | 4 | |a leptospirosis |
| 650 | 0 | 4 | |a Malaysia |
| 650 | 0 | 4 | |a male |
| 650 | 0 | 4 | |a murine typhus |
| 650 | 0 | 4 | |a Murine typhus |
| 650 | 0 | 4 | |a nonhuman |
| 650 | 0 | 4 | |a nucleic acid analysis |
| 650 | 0 | 4 | |a rash |
| 650 | 0 | 4 | |a rickettsiosis |
| 650 | 0 | 4 | |a RNA 16S |
| 650 | 0 | 4 | |a serology |
| 650 | 0 | 4 | |a Serology |
| 650 | 0 | 4 | |a suburban area |
| 650 | 0 | 4 | |a thrombocytopenia |
| 650 | 0 | 4 | |a urban area |
| 856 | |z View Fulltext in Publisher |u https://doi.org/10.3390/tropicalmed4010023 | ||
| 856 | |z View in Scopus |u https://www.scopus.com/inward/record.uri?eid=2-s2.0-85075800736&doi=10.3390%2ftropicalmed4010023&partnerID=40&md5=6b7595b2c8956b81b1e74a7a95961881 | ||
| 520 | 3 | |a Murine typhus is a rarely diagnosed cause of acute febrile illness in Malaysia, and its true disease burden is unknown. We report a case of an acute murine typhus infection in a patient living in a small city in Peninsular Malaysia, presenting with fever, rash, and headache. Unresponsive to the initial empirical treatment for leptospirosis, he showed a rapid response to doxycycline when murine typhus was diagnosed later. This case highlights the importance of considering murine typhus as a diagnostic in cases of acute febrile illness in urban and sub-urban areas, such as that of in Peninsular Malaysia. © 2019 by the authors. | |
| 700 | 1 | 0 | |a Blacksell, S.D. |e author |
| 700 | 1 | 0 | |a Chotivanich, K. |e author |
| 700 | 1 | 0 | |a Hanboonkunupakarn, B. |e author |
| 700 | 1 | 0 | |a Paris, D.H. |e author |
| 700 | 1 | 0 | |a Pukrittayakamee, S. |e author |
| 700 | 1 | 0 | |a Sonthayanon, P. |e author |
| 700 | 1 | 0 | |a Sujariyakul, P. |e author |
| 700 | 1 | 0 | |a Tanganuchitcharnchai, A. |e author |
| 700 | 1 | 0 | |a Yuhana, Y. |e author |
| 773 | |t Tropical Medicine and Infectious Disease |x 24146366 (ISSN) |g 4 1 | ||