Giving Drugs a Second Chance: Antibacterial and Antibiofilm Effects of Ciclopirox and Ribavirin against Cystic Fibrosis Pseudomonas aeruginosa Strains

Giving Drugs a Second Chance: Antibacterial and Antibiofilm Effects of Ciclopirox and Ribavirin against Cystic Fibrosis Pseudomonas aeruginosa Strains

Drug repurposing is an attractive strategy for developing new antibacterial molecules. Herein, we evaluated the in vitro antibacterial, antibiofilm, and antivirulence activities of eight FDA-approved “non-antibiotic” drugs, comparatively to tobramycin, against selected Pseudomonas aeruginosa strains...

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Bibliographic Details
Main Authors: De Fabritiis, S. (Author), Di Bonaventura, G. (Author), Di Nicola, M. (Author), Lupetti, V. (Author), Piccirilli, A. (Author), Pompilio, A. (Author), Porreca, A. (Author)
Format: Article
Language:English
Published: MDPI 2022
Subjects:
biofilm
cystic fibrosis
drug repurposing
Pseudomonas aeruginosa
Online Access:View Fulltext in Publisher

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