Elevated Expression of the Immune Checkpoint Ligand CD276 (B7‐H3) in Urothelial Carcinoma Cell Lines Correlates Negatively with the Cell Proliferation

Elevated Expression of the Immune Checkpoint Ligand CD276 (B7‐H3) in Urothelial Carcinoma Cell Lines Correlates Negatively with the Cell Proliferation

The cell surface molecule CD276 (B7‐H3) is an immune checkpoint antigen. The elevated expression of CD276 on tumors contributes to the suppression of anti‐tumor T‐cell responses and correlates with poor prognosis. Methods: The expression of CD276 was explored in vitro on eight urothelial carcinoma c...

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Bibliographic Details
Main Authors: Abruzzese, T. (Author), Aicher, W.K (Author), Amend, B. (Author), Bock, C. (Author), Fend, F. (Author), Harland, N. (Author), Maurer, F.B (Author), Montes‐mojarro, I.A (Author), Stenzl, A. (Author)
Format: Article
Language:English
Published: MDPI 2022
Subjects:
bladder cancer stem cell
CD276
immune checkpoint antigen
urothelial carcinoma
Online Access:View Fulltext in Publisher

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