Atovaquone: An Inhibitor of Oxidative Phosphorylation as Studied in Gynecologic Cancers

Atovaquone: An Inhibitor of Oxidative Phosphorylation as Studied in Gynecologic Cancers

Oxidative phosphorylation is an active metabolic pathway in cancer. Atovaquone is an oral medication that inhibits oxidative phosphorylation and is FDA-approved for the treatment of malaria. We investigated its potential anti-cancer properties by measuring cell proliferation in 2D culture. The clini...

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Bibliographic Details
Main Authors: Barroilhet, L.M (Author), Dominguez, J.M.A (Author), Ericksen, S.S (Author), Felder, M. (Author), Kapur, A. (Author), Mehta, G. (Author), Mehta, P. (Author), Nayak, A. (Author), Palecek, S.P (Author), Patankar, M. (Author), Simmons, A.D (Author), Stenerson, Z. (Author)
Format: Article
Language:English
Published: MDPI 2022
Subjects:
metabolism
mitochondria
oxidative phosphorylation
Online Access:View Fulltext in Publisher

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