Arginine Methyltransferase PRMT7 Deregulates Expression of RUNX1 Target Genes in T-Cell Acute Lymphoblastic Leukemia

Arginine Methyltransferase PRMT7 Deregulates Expression of RUNX1 Target Genes in T-Cell Acute Lymphoblastic Leukemia

T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy with no well-established prognostic biomarkers. We examined the expression of protein arginine methyltransferases across hematological malignancies and discovered high levels of PRMT7 mRNA in T-ALL, particularly in...

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Bibliographic Details
Main Authors: Haapaniemi, P. (Author), Heinäniemi, M. (Author), Hyvärinen, N. (Author), Kauko, O. (Author), Laukkanen, S. (Author), Lohi, O. (Author), Mäkinen, A. (Author), Nikkilä, A. (Author), Oksa, L. (Author), Rokka, A. (Author), Seki, M. (Author), Takita, J. (Author)
Format: Article
Language:English
Published: MDPI 2022
Subjects:
arginine methylation
leukemia
PRMT7
RUNX1
T-ALL
Online Access:View Fulltext in Publisher

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