Canonical Bone Morphogenetic Protein Signaling Regulates Expression of Aquaporin-4 and Its Anchoring Complex in Mouse Astrocytes

Canonical Bone Morphogenetic Protein Signaling Regulates Expression of Aquaporin-4 and Its Anchoring Complex in Mouse Astrocytes

Aquaporin-4 (AQP4) is the predominant water channel in the brain; it is enriched in astrocytic foot processes abutting vessels where it is anchored through an interaction with the dystrophin-associated protein (DAP) complex. Enhanced expression with concomitant mislocalization of AQP4 along astrocyt...

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Bibliographic Details
Main Authors: Amiry-Moghaddam, M. (Author), Ottersen, O.P (Author), Roybon, L. (Author), Savchenko, E. (Author), Skauli, N. (Author)
Format: Article
Language:English
Published: Frontiers Media S.A. 2022
Subjects:
aquaporin-4
astrocyte
bone morphogenetic protein
dystrophin
Smad1/5/9
Online Access:View Fulltext in Publisher

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