Chronic Distress in Male Mice Impairs Motivation Compromising Both Effort and Reward Processing With Altered Anterior Insular Cortex and Basolateral Amygdala Neural Activation
In humans and mammals, effort-based decision-making for monetary or food rewards paradigms contributes to the study of adaptive goal-directed behaviours acquired through reinforcement learning. Chronic distress modelled by repeated exposure to glucocorticoids in rodents induces suboptimal decision-m...
Main Authors: | Cabeza, L. (Author), Cramoisy, S. (Author), Fellmann, D. (Author), Haffen, E. (Author), Houdayer, C. (Author), Peterschmitt, Y. (Author), Ramadan, B. (Author), Risold, P.-Y (Author) |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021
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Subjects: | |
Online Access: | View Fulltext in Publisher |
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