Sex-Specific Social Behavior and Amygdala Proteomic Deficits in Foxp2+/− Mutant Mice

Sex-Specific Social Behavior and Amygdala Proteomic Deficits in Foxp2+/− Mutant Mice

In humans, mutations in the transcription factor encoding gene, FOXP2, are associated with language and Autism Spectrum Disorders (ASD), the latter characterized by deficits in social interactions. However, little is known regarding the function of Foxp2 in male or female social behavior. Our previo...

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Bibliographic Details
Main Authors: Banerjee, P. (Author), Corbin, J.G (Author), Goodrich, M. (Author), Hernandez-Pineda, D. (Author), Herrero, M.J (Author), Matos, H.Y (Author), Panigrahi, A. (Author), Smith, N.A (Author), Wang, L. (Author)
Format: Article
Language:English
Published: Frontiers Media S.A. 2021
Subjects:
aggression
animal cell
animal experiment
animal tissue
Article
cell communication
controlled study
dopamine
female
Foxp2
Foxp2 gene
gene mutation
loss of function mutation
male
mating
medial amygdala
medial amygdala (MeA)
mouse
nerve cell network
nonhuman
parental behavior
protein expression
proteomics
sex difference
sex-specific differences
smelling
social behavior
social interaction
transcription factor FOXP2
Online Access:View Fulltext in Publisher

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