Reduced Hippocampal GABA+ Is Associated With Poorer Episodic Memory in Healthy Older Women: A Pilot Study

Reduced Hippocampal GABA+ Is Associated With Poorer Episodic Memory in Healthy Older Women: A Pilot Study

Background: The current pilot study was designed to examine the association between hippocampal γ-aminobutyric acid (GABA) concentration and episodic memory in older individuals, as well as the impact of two major risk factors for Alzheimer’s disease (AD)—female sex and Apolipoprotein ε4 (ApoE ε4) g...

Full description

Bibliographic Details
Main Authors:	Brickman, A.M (Author), Buyukturkoglu, K. (Author), Chen, L. (Author), Eich, T.S (Author), Guo, J. (Author), Igwe, K. (Author), Irimia, A. (Author), Jiménez-Balado, J. (Author), Klem, L. (Author), Ycaza Herrera, A. (Author)
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021
Subjects:	4 aminobutyric acid 4 aminobutyric acid metabolism adult aged Alzheimer disease Alzheimer’s disease amnesia apolipoprotein E4 apolipoprotein ε4 Article brain size choline cohort analysis creatine directed forgetting task disease association episodic memory female fluid-attenuated inversion recovery imaging GABA glutamic acid glutamine heterozygote hippocampus homocarnosine human human experiment image analysis image segmentation male memory test middle aged n acetylaspartic acid neuroimaging normal human nuclear magnetic resonance spectroscopy pilot study proton nuclear magnetic resonance sex γ-aminobutyric acid
Online Access:	View Fulltext in Publisher

Similar Items

Reduced Hippocampal GABA+ Is Associated With Poorer Episodic Memory in Healthy Older Women: A Pilot Study
by: Joan Jiménez-Balado, et al.
Published: (2021-08-01)

The use of deuterium-labeled gamma-aminobutyric (D6-GABA) to study uptake, translocation, and metabolism of exogenous GABA in plants
by: Faraj Hijaz, et al.
Published: (2020-02-01)

Comparative study of striatum GABA concentrations and magnetic resonance spectroscopic imaging in Parkinson's disease monkeys
by: Lixuan Huang, et al.
Published: (2019-08-01)

GABA transaminase deficiency. Case report and literature review
by: Amira Oshi, et al.
Published: (2021-03-01)

Anterior cingulate gamma‐aminobutyric acid concentrations and electroconvulsive therapy
by: Vera J. Erchinger, et al.
Published: (2020-11-01)

In vivo magnetic resonance studies reveal neuroanatomical and neurochemical abnormalities in the serine racemase knockout mouse model of schizophrenia
by: Matthew D. Puhl, et al.
Published: (2015-01-01)

Treatment effects on neurometabolite levels in schizophrenia: A meta-analysis dataset of proton magnetic resonance spectroscopy
by: Manabu Kubota, et al.
Published: (2020-08-01)

Biosynthesis of Polyamide 4, a Biobased and Biodegradable Polymer
by: IWAN SASKIAWAN
Published: (2010-08-01)

Gaba neurobiology and C1sup(-) conductance on insect muscle
by: Scott, R. H.
Published: (1984)

GABA and glutamate mimetics
by: Namwindwa, Ernest Sinvula
Published: (1987)

Involvement of upregulation of miR-210 in a rat epilepsy model
by: Chen L, et al.
Published: (2016-07-01)

On the functional role of striatal and anterior cingulate GABA+ in stimulus-response binding
by: Beste, C., et al.
Published: (2021)

INHIBITORY NEUROTRANSMITTERS AND THEIR INFLUENCE ON TUMOR IN PATIENTS WITH GLIOMAS
by: A. V. Kartashev, et al.
Published: (2016-02-01)

Effect of Curcumin on the Hypothalamus Levels of the Potent Inhibitory Neurotransmitter ,Gamma aminobutyric acid
by: Shokoufe Nikpour Moghaddam, et al.
Published: (2015-01-01)

Preliminary study on BABA-induced resistance to alkaline stress in tobacco
by: YOU Benwu, et al.
Published: (2017-02-01)

The identification of a novel protein interacting with GABAâ†A receptors using the yeast two-hybrid system
by: Wilkinson, Helen Louise
Published: (2000)

Towards a Synthesis of Vigabatrin Using Glycal Chemistry
by: I. Aidhen, et al.
Published: (2005-08-01)

Antiepileptic Potential of Matrine via Regulation the Levels of Gamma-Aminobutyric Acid and Glutamic Acid in the Brain
by: Jun Xiang, et al.
Published: (2013-12-01)

Muscimol Directly Activates the TREK-2 Channel Expressed in GABAergic Neurons through Its N-Terminus
by: Eun-Jin Kim, et al.
Published: (2021-08-01)

GABA, Glutamate, and NAA Levels in the Deep Cerebellar Nuclei of Essential Tremor Patients
by: Arthur W. G. Buijink, et al.
Published: (2021-05-01)

Excitatory and inhibitory responses in the brain to experimental pain: A systematic review of MR spectroscopy studies
by: Jessica Archibald, et al.
Published: (2020-07-01)

Optimization of the MEGA-PRESS Sequence for Detection of γ-Aminobutyric Acid in Vivo
by: HUA Rui, et al.
Published: (2018-06-01)

Gamma-Aminobutyric Acid Levels in the Anterior Cingulate Cortex of Perimenopausal Women With Depression: A Magnetic Resonance Spectroscopy Study
by: Dan Wang, et al.
Published: (2019-08-01)

Perceived Stress, Cortical GABA, and Functional Connectivity Correlates: A Hypothesis-Generating Preliminary Study
by: Busler, J.N, et al.
Published: (2022)

Effects of γ-aminobutyric acid on feed intake, growth performance and expression of related genes in growing lambs
by: D.M. Wang, et al.
Published: (2015-01-01)

Intracortical Inhibition Assessed with Paired-Pulse Transcranial Magnetic Stimulation is Modulated during Shortening and Lengthening Contractions in Young and Old Adults
by: George M. Opie, et al.
Published: (2016-03-01)

Lilium davidii extract alleviates p‑chlorophenylalanine‑induced insomnia in rats through modification of the hypothalamic-related neurotransmitters, melatonin and homeostasis of the hypothalamic-pituitary-adrenal axis
by: Yanpo Si, et al.
Published: (2020-01-01)

Gamma-aminobutyric acid mediates nicotine biosynthesis in tobacco under flooding stress
by: Xiaoming Zhang, et al.
Published: (2016-02-01)

Partial Cloning and Nucleotide Sequencing of Glutamate Decarboxylase Gene Isoform 65 from Human Brain
by: Abolghasem Esmaeili, et al.
Published: (2015-04-01)

Acidification and γ-aminobutyric acid independently alter kairomone-induced behaviour
by: Corie L. Charpentier, et al.
Published: (2016-01-01)

REDUCTION OF HERBICIDE AND WATER STRESS IN SPRING BARLEY BY REGULATORS OF POLYAMINE BIOSYNTHESIS
by: Pavol Trebichalský, et al.
Published: (2014-02-01)

Hexonic derivatives as human GABA-AT inhibitors: A molecular docking approach
by: Dharmaraj Senthilkumar, et al.
Published: (2015-01-01)

Temporal coding at the immature depolarizing GABAergic synapse
by: Guzel Valeeva, et al.
Published: (2010-07-01)

Synergy of piracetam and aminalon in the cerebroprotective effect of olatropyl.
by: V. I. Mamchur, et al.
Published: (2018-11-01)

The potential role of pancreatic γ-aminobutyric acid (GABA) in diabetes mellitus: A critical reappraisal
by: Hayder M Al-Kuraishy, et al.
Published: (2021-01-01)

Eicosapentaenoic Acid Is Associated with Decreased Incidence of Alzheimer’s Dementia in the Oldest Old
by: Debora Melo van Lent, et al.
Published: (2021-01-01)

Magnetic Resonance Spectroscopy in Canavan’s Disease
by: J Gordon Millichap
Published: (1991-07-01)

Effect of some induce chemical and biological agents against (Tilletia tritici (Bjerk) and T.laevis (Kühn) causal agents of wheat Common bunt disease
by: Baghdad Science Journal
Published: (2016-06-01)

Effects of white rice containing enriched gamma-aminobutyric acid on blood pressure
by: Mie Nishimura, et al.
Published: (2016-01-01)

Effective neuroprotection and organ protection: activation of the endogenous mechanisms of sanogenesis
by: R. G. Esin, et al.
Published: (2020-06-01)

Cannot write session to /tmp/vufind_sessions/sess_j63cs6t22isa2bbcvvt4dfel82