Reduced Hippocampal GABA+ Is Associated With Poorer Episodic Memory in Healthy Older Women: A Pilot Study

Reduced Hippocampal GABA+ Is Associated With Poorer Episodic Memory in Healthy Older Women: A Pilot Study

Background: The current pilot study was designed to examine the association between hippocampal γ-aminobutyric acid (GABA) concentration and episodic memory in older individuals, as well as the impact of two major risk factors for Alzheimer’s disease (AD)—female sex and Apolipoprotein ε4 (ApoE ε4) g...

Full description

Bibliographic Details
Main Authors: Brickman, A.M (Author), Buyukturkoglu, K. (Author), Chen, L. (Author), Eich, T.S (Author), Guo, J. (Author), Igwe, K. (Author), Irimia, A. (Author), Jiménez-Balado, J. (Author), Klem, L. (Author), Ycaza Herrera, A. (Author)
Format: Article
Language:English
Published: Frontiers Media S.A. 2021
Subjects:
4 aminobutyric acid
4 aminobutyric acid metabolism
adult
aged
Alzheimer disease
Alzheimer’s disease
amnesia
apolipoprotein E4
apolipoprotein ε4
Article
brain size
choline
cohort analysis
creatine
directed forgetting task
disease association
episodic memory
female
fluid-attenuated inversion recovery imaging
GABA
glutamic acid
glutamine
heterozygote
hippocampus
homocarnosine
human
human experiment
image analysis
image segmentation
male
memory test
middle aged
n acetylaspartic acid
neuroimaging
normal human
nuclear magnetic resonance spectroscopy
pilot study
proton nuclear magnetic resonance
sex
γ-aminobutyric acid
Online Access:View Fulltext in Publisher

Internet

View Fulltext in Publisher

Similar Items