Wound healing bioactivity of curcuma longa linn

• Main Authors: Hardiyanti, R. (Author), Irham, W.H (Author)
• Format: Article
• Language: English
• Published: Rasayan Journal of Chemistry, c/o Dr. Pratima Sharma 2021
• Subjects: Antibacterial activity; Curcuma longa linn; FTIR analysis; Phytochemical screening; Wound healing bioactivity
• Online Access: View Fulltext in Publisher

 Traditional people of Sumatera Utara, Indonesia, mostly used Curcuma Longa Linn as a wound medicine. This research aims to see the wound healing bioactivity of Curcuma Longa Linn. Identify Curcuma Longa Linn content with the phytochemical screening; the displayed results contain alkaloid, terpenoid/steroid, phenolic, and saponin. FTIR analysis indicated the presence of secondary metabolite. The presence of alkaloids relieved due to the NH stretching peaks at 1579.56 cm-1, terpenoid due to the CH group peak at 2926.58 cm-1, 2106.17 cm-1, and reinforced with peaks at 971.15 cm-1 and 871.49 cm-1 . O-H stretching peaks at 3316.33 cm-1, 1515.34 cm-1, 971.15 cm-1 were indicated polyphenols. Antibacterial test using Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus the result of Antibacterial test shown the secondary metabolite of Curcuma Longa Linn has high antibacterial activity. This compound play a role in increasing collagen synthesis early, which can function to restore wound tissue structure and support faster wound healing. © 2021, Rasayan Journal of Chemistry, c/o Dr. Pratima Sharma. All rights reserved.