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| LEADER |
01349nam a2200217Ia 4500 |
| 001 |
10.31788-RJC.2021.1445943 |
| 008 |
220427s2021 CNT 000 0 und d |
| 020 |
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|a 09741496 (ISSN)
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| 245 |
1 |
0 |
|a STRATEGIC APPROACHES TO THE SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION OF SUBSTITUTED PIPERAZINYL-IMIDAZOLE CONJUGATES
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| 260 |
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0 |
|b Rasayan Journal of Chemistry, c/o Dr. Pratima Sharma
|c 2021
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| 856 |
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|z View Fulltext in Publisher
|u https://doi.org/10.31788/RJC.2021.1445943
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| 520 |
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|a A series of hybrid molecules bearing 5-nitroimidazole linked with substituted piperazine molecules have been synthesized. The cytotoxicity of all the synthesized compounds has been evaluated on HEK293 cells with the help of MTT assay. It was found that the treatment of these compounds shows a variable toxicity profile for HEK293 cells. The results of cytotoxicity showed that in the tested concentration range, compound NJ3, NJ5, NJ8 and NJ10 show considerable cytotoxicity towards HEK293 cells. © 2021, Rasayan Journal of Chemistry, c/o Dr. Pratima Sharma. All rights reserved.
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|a Cell Viability Assay
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|a Cytotoxicity
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| 650 |
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|a MTT Assay
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| 650 |
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|a Nitroimidazole
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| 650 |
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|a Piperazine
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| 700 |
1 |
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|a Azam, A.
|e author
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| 700 |
1 |
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|a Gupta, J.
|e author
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1 |
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|a Inam, A.
|e author
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| 773 |
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|t Rasayan Journal of Chemistry
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