Acute application of Centella asiatica extract enhanced AMPAR-mediated postsynaptic currents in rat entorhinal cortex

Acute application of Centella asiatica extract enhanced AMPAR-mediated postsynaptic currents in rat entorhinal cortex

Centella asiatica is notable for its wide range of biological activities beneficial to human health, particularly its cognitive enhancement and neuroprotective effects. The-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors are ionotropic glutamate receptors mediating fast excitatory neuro...

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Bibliographic Details
Main Authors: Abdullah, J.M (Author), Chuang, H.G (Author), Ismail, N.H (Author), Mohamad, H. (Author), Muhammad, T.S.T (Author), Muthuraju, S. (Author), Reza, F. (Author), Senik, M.H (Author), Wong, J.H (Author), Yusof, S.R (Author), Zhang, J. (Author)
Format: Article
Language:English
Published: IMR Press Limited, 2020
Subjects:
alpha amino 3 hydroxy 5 methyl 4 isoxazolepropionic acid receptor
AMPA receptor
AMPAR
animal
animal experiment
animal tissue
Animals
Article
asiatic acid
asiaticoside
bioavailability
brain slice
Centella asiatica
Centella asiatica extract
cognition
controlled study
drug effect
entorhinal cortex
Entorhinal Cortex
excitatory postsynaptic potential
Excitatory Postsynaptic Potentials
follow up
hippocampus
ionotropic receptor
long term potentiation
low drug dose
male
neuromodulation
nonhuman
nootropic agent
Nootropic Agents
patch clamp technique
Patch-Clamp Techniques
pyramidal nerve cell
rat
Rats
Receptors, AMPA
triterpene
Triterpenes
unclassified drug
whole cell patch clamp
whole-cell patch-clamp
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