Multiple endocrine neoplasia type 1 with brown tumors as first manifestation in a patient with pituitary adenoma: A case report

Introduction: Multiple endocrine neoplasia type 1 (MEN 1) is an infrequent autosomal dominant hereditary syndrome. Common manifestations are related to hypercalcemia, which is caused by primary hyperparathyroidism (PHPT). Brown tumors are infrequent as initial presentation of PHPT associated with ME...

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Bibliographic Details
Main Authors: Chambergo-Michilot, D. (Author), Gutierrez, G.E (Author), Ibarcena-Llerena, C.V (Author), Manrique-Franco, K. (Author)
Format: Article
Language:English
Published: Modestum LTD 2022
Subjects:
Online Access:View Fulltext in Publisher
LEADER 01760nam a2200229Ia 4500
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008 220718s2022 CNT 000 0 und d
020 |a 25163507 (ISSN) 
245 1 0 |a Multiple endocrine neoplasia type 1 with brown tumors as first manifestation in a patient with pituitary adenoma: A case report 
260 0 |b Modestum LTD  |c 2022 
856 |z View Fulltext in Publisher  |u https://doi.org/10.29333/ejgm/12077 
520 3 |a Introduction: Multiple endocrine neoplasia type 1 (MEN 1) is an infrequent autosomal dominant hereditary syndrome. Common manifestations are related to hypercalcemia, which is caused by primary hyperparathyroidism (PHPT). Brown tumors are infrequent as initial presentation of PHPT associated with MEN 1. It occurs in less than 2% of MEN 1 population. Results: A 36-year-old woman started the disease 25 years ago in an insidious and progressive manner. She presented a soft tumor in the left malar region that progressively increased in volume. We treated recurrent multiple brown tumors in a patient with PHPT and pituitary adenoma. Conclusion: The follow-up was demanding and multidisciplinary. The long-term prognosis is uncertain; therefore, close monitoring of the patient should be carried out through clinical, laboratory and imaging evaluation. © 2022 by Author/s and Licensed by Modestum. 
650 0 4 |a case reports 
650 0 4 |a multiple endocrine neoplasia type 1 
650 0 4 |a osteitis fibrosa cystica 
650 0 4 |a pituitary neoplasms 
650 0 4 |a recklinghausen’s disease of bone 
700 1 |a Chambergo-Michilot, D.  |e author 
700 1 |a Gutierrez, G.E.  |e author 
700 1 |a Ibarcena-Llerena, C.V.  |e author 
700 1 |a Manrique-Franco, K.  |e author 
773 |t Electronic Journal of General Medicine