Systemic VEGF-A neutralization ameliorates diet-induced metabolic dysfunction

Systemic VEGF-A neutralization ameliorates diet-induced metabolic dysfunction

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The vascular endothelial growth factor (VEGF) family of cytokines are important regulators of angiogenesis that have emerged as important targets for the treatment of obesity. While serum VEGF levels rise during obesity, recent studies using genetic models provide conflicting evidence as to whether...

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Main Authors: Andrikopoulos, S. (Author), Burchfield, J.G (Author), Cogger, V.C (Author), Cooney, G.J (Author), Fazakerley, D.J (Author), Gamble, J.R (Author), James, D.E (Author), Kang, M.-J (Author), Kolumam, G. (Author), Le Couteur, D.G (Author), Mangiafico, S.P (Author), Meoli, C.C (Author), Mikolaizak, A.S (Author), Mohamad, M. (Author), Pant, H. (Author), Powter, E. (Author), Stöckli, J. (Author), Van Bruggen, N. (Author), Wu, L.E (Author), Xirouchaki, C.E (Author)
Format: Article
Language:English
Published: American Diabetes Association Inc. 2014
Subjects:
Adiposity
Animal Feed
Animals
Antibodies
Dietary Fats
Glucose
Homeostasis
Immunoglobulin G
Insulin
Insulin Resistance
Liver
Male
Mice
Obesity
Signal Transduction
Vascular Endothelial Growth Factor A
Online Access:View Fulltext in Publisher
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