The relationship of lamins with epigenetic factors during aging
The key factor of genome instability during aging is transposon dysregulation. This may be due to senile changes in the expression of lamins, which epigenetically modulate transposons. Lamins directly physically interact with transposons. Epigenetic regulators such as SIRT7, BAF, and microRNA can al...
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| Format: | Article |
| Language: | English |
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Institute of Cytology and Genetics of Siberian Branch of the Russian Academy of Sciences
2022
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| Subjects: | |
| Online Access: | View Fulltext in Publisher |