Discrete mechanical model of lamellipodial actin network implements molecular clutch mechanism and generates arcs and microspikes
Mechanical forces, actin filament turnover, and adhesion to the extracellular environment regulate lamellipodial protrusions. Computational and mathematical models at the continuum level have been used to investigate the molecular clutch mechanism, calculating the stress profile through the lamellip...
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science
2021
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| Subjects: | |
| Online Access: | View Fulltext in Publisher |