Antibacterial activity of hoya diversifolia ethanolic leaves extract

The rapid emergence of resistance bacteria toward various antibiotics may associate with higher medical cost and increase mortality rate. Hoya diversifolia was used to cure skin diseases and alleviate rheumatism pain. The aim of this study is to evaluate in vitro antibacterial properties of H. diver...

Full description

Bibliographic Details
Main Authors: Ismail, S. (Author), Ismail, W.I (Author), Lamin, R.A.C (Author), Mail, M.H (Author), Rahim, N.Ab (Author), Roslan, M.N.F (Author)
Format: Article
Language:English
Published: Oriental Scientific Publishing Company 2019
Subjects:
Online Access:View Fulltext in Publisher
View in Scopus
LEADER 03081nam a2200637Ia 4500
001 10.13005-bpj-1710
008 220121s2019 CNT 000 0 und d
020 |a 09746242 (ISSN) 
245 1 0 |a Antibacterial activity of hoya diversifolia ethanolic leaves extract 
260 0 |b Oriental Scientific Publishing Company  |c 2019 
650 0 4 |a alcohol 
650 0 4 |a alkaloid derivative 
650 0 4 |a ampicillin 
650 0 4 |a anthraquinone derivative 
650 0 4 |a Antibacterial 
650 0 4 |a antibacterial activity 
650 0 4 |a antibiotic agent 
650 0 4 |a Article 
650 0 4 |a Bacillus cereus 
650 0 4 |a bacterial strain 
650 0 4 |a controlled study 
650 0 4 |a Disc diffussion 
650 0 4 |a disk diffusion 
650 0 4 |a Escherichia coli 
650 0 4 |a gentamicin 
650 0 4 |a Hoya diversifolia 
650 0 4 |a Hoya diversifolia extract 
650 0 4 |a in vitro study 
650 0 4 |a lupeol 
650 0 4 |a methicillin resistant Staphylococcus aureus 
650 0 4 |a minimum inhibitory concentration 
650 0 4 |a Minimum inhibitory concentration 
650 0 4 |a nonhuman 
650 0 4 |a plant extract 
650 0 4 |a plant leaf 
650 0 4 |a saponin derivative 
650 0 4 |a scanning electron microscopy 
650 0 4 |a sitosterol 
650 0 4 |a squalene 
650 0 4 |a Staphylococcus aureus 
650 0 4 |a surface property 
650 0 4 |a tannin derivative 
650 0 4 |a traditional medicine 
650 0 4 |a unclassified drug 
650 0 4 |a vancomycin 
650 0 4 |a zone of inhibition 
856 |z View Fulltext in Publisher  |u https://doi.org/10.13005/bpj/1710 
856 |z View in Scopus  |u https://www.scopus.com/inward/record.uri?eid=2-s2.0-85069556691&doi=10.13005%2fbpj%2f1710&partnerID=40&md5=2248d5c10e83af2740eb5be32d5f1f65 
520 3 |a The rapid emergence of resistance bacteria toward various antibiotics may associate with higher medical cost and increase mortality rate. Hoya diversifolia was used to cure skin diseases and alleviate rheumatism pain. The aim of this study is to evaluate in vitro antibacterial properties of H. diversifolia ethanolicleaves extract against several Gram positive and Gram negative bacteria. The antibacterial study was determined based on pattern of inhibition zones using disc diffusion assay and also minimal inhibitory concentration (MIC). It is shown that the extract can inhibit the growth of methicillin-resistant Staphylococcus aureus,Escherichia coliandBacillus cereus.The lowest MIC values of extract were 25 mg/mL for MRSA and E. coli as well as 100 mg/mL for B. cereus at 24 and 48 hours of incubation period. The plant had potential to act as antibacterial agent that can be applied in pharmaceutical and cosmetic fields. © 2019 Oriental Scientific Publishing Company. All rights reserved. 
700 1 0 |a Ismail, S.  |e author  
700 1 0 |a Ismail, W.I.  |e author  
700 1 0 |a Lamin, R.A.C.  |e author  
700 1 0 |a Mail, M.H.  |e author  
700 1 0 |a Rahim, N.Ab.  |e author  
700 1 0 |a Roslan, M.N.F.  |e author  
773 |t Biomedical and Pharmacology Journal  |x 09746242 (ISSN)  |g 12 2, 857-862