Computational design of highly stable and soluble alcohol dehydrogenase for NADPH regeneration

Computational design of highly stable and soluble alcohol dehydrogenase for NADPH regeneration

Nicotinamide adenine dinucleotide phosphate (NADPH), as a well-known cofactor, is widely used in the most of enzymatic redox reactions, playing an important role in industrial catalysis. However, the absence of a comparable method for efficient NADP+ to NADPH cofactor regeneration radically impairs...

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Bibliographic Details
Main Authors:	Deng, T. (Author), Wang, Z. (Author), Wu, J. (Author), Xu, J. (Author), Yang, L. (Author), Yu, H. (Author), Zhang, H. (Author), Zhou, H. (Author)
Format:	Article
Language:	English
Published:	Springer Science and Business Media Deutschland GmbH 2021
Subjects:	Alcohol dehydrogenase Chiral alcohols Computational design NADPH regeneration Soluble expression
Online Access:	View Fulltext in Publisher

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