An integrative in-silico analysis discloses a novel molecular subset of colorectal cancer possibly eligible for immune checkpoint immunotherapy

An integrative in-silico analysis discloses a novel molecular subset of colorectal cancer possibly eligible for immune checkpoint immunotherapy

Background: Historically, the molecular classification of colorectal cancer (CRC) was based on the global genomic status, which identified microsatellite instability in mismatch repair (MMR) deficient CRC, and chromosomal instability in MMR proficient CRC. With the introduction of immune checkpoint...

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Bibliographic Details
Main Authors: Belardinilli, F. (Author), Giannini, G. (Author), Licursi, V. (Author), Paci, P. (Author), Sibilio, P. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2022
Subjects:
Colorectal cancer
Immunoinformatics
Immunotherapy
Meta-analysis
Multi-omics
Online Access:View Fulltext in Publisher

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