Identifying clinical subtypes in sepsis-survivors with different one-year outcomes: a secondary latent class analysis of the FROG-ICU cohort

Identifying clinical subtypes in sepsis-survivors with different one-year outcomes: a secondary latent class analysis of the FROG-ICU cohort

BACKGROUND: Late mortality risk in sepsis-survivors persists for years with high readmission rates and low quality of life. The present study seeks to link the clinical sepsis-survivors heterogeneity with distinct biological profiles at ICU discharge and late adverse events using an unsupervised ana...

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Main Authors: Acton, E. (Author), Brochard, L. (Author), CCCTBG trans-trial group study for InFACT - the International Forum for Acute Care Trialists (Author), Del Sorbo, L. (Author), Dos Santos, C.C (Author), Feliot, E. (Author), Ferguson, N. (Author), FROG-ICU (Author), Gayat, E. (Author), Herridge, M. (Author), Jüni, P. (Author), Kennedy, J.N (Author), Lawler, P.R (Author), Lebovic, G. (Author), Marshall, J.C (Author), Mebazaa, A. (Author), Sharma, D. (Author), Soussi, S. (Author), Xu, W. (Author)
Format: Article
Language:English
Published: NLM (Medline) 2022
Subjects:
Biomarkers
Latent profile analysis
Mixture modeling
Personalized medicine
Post-intensive care syndrome (PICS)
Prognostic enrichment
Sepsis
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