TPI1 activates the PI3K/AKT/mTOR signaling pathway to induce breast cancer progression by stabilizing CDCA5

TPI1 activates the PI3K/AKT/mTOR signaling pathway to induce breast cancer progression by stabilizing CDCA5

Background: Triosephosphate isomerase 1 (TPI1), as a key glycolytic enzyme, is upregulated in multiple cancers. However, expression profile and regulatory mechanism of TPI1 in breast cancer (BRCA) remain mysterious. Methods: Western blotting and immunohistochemistry (IHC) assays were used to investi...

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Bibliographic Details
Main Authors:	Chen, F. (Author), Chen, X. (Author), Cui, Y. (Author), Guo, Y. (Author), Jin, X. (Author), Lei, M. (Author), Sun, W. (Author), Wang, D. (Author)
Format:	Article
Language:	English
Published:	BioMed Central Ltd 2022
Subjects:	CDCA5 Epithelial–mesenchymal transformation (EMT) Glycolysis PI3K/AKT/mTOR TPI1
Online Access:	View Fulltext in Publisher

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