Circular RNA EIF4G3 suppresses gastric cancer progression through inhibition of β-catenin by promoting δ-catenin ubiquitin degradation and upregulating SIK1

Circular RNA EIF4G3 suppresses gastric cancer progression through inhibition of β-catenin by promoting δ-catenin ubiquitin degradation and upregulating SIK1

Background: Increasing studies suggest that circular RNAs (circRNAs) are critical regulators of cancer development and progression. However, the biological roles and mechanisms of circRNAs in gastric cancer (GC) remain largely unknown. Methods: We identified the differentially expressed circRNAs in...

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Bibliographic Details
Main Authors: Cai, H. (Author), Chen, Y. (Author), Fu, M. (Author), Gu, J. (Author), Jiang, J. (Author), Qian, H. (Author), Shi, H. (Author), Wang, M. (Author), Xu, W. (Author), Zang, X. (Author), Zhang, X. (Author), Zhang, Y. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2022
Subjects:
Circular RNA
Gastric cancer
SIK1
TRIM25
δ-catenin
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