Long-term effectiveness and safety of ustekinumab in bio-naïve and bio-experienced anti-tumor necrosis factor patients with Crohn’s disease: a real-world multicenter Brazilian study

Long-term effectiveness and safety of ustekinumab in bio-naïve and bio-experienced anti-tumor necrosis factor patients with Crohn’s disease: a real-world multicenter Brazilian study

Background: The effectiveness of ustekinumab (UST) in the treatment of Crohn’s disease (CD) has been demonstrated in the pivotal Phase 3 UNITI 1 and 2 and IM-UNITI studies in both anti-TNF-naïve and anti-TNF-exposed patients. Given the selective nature of pivotal trial designs, real-world effective...

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Main Authors: Alves Junior, A.J.T (Author), Ambrogini Junior, O. (Author), Bafutto, M. (Author), Bertges, E.R (Author), Boratto, S.F (Author), Carvalho, N.S (Author), Chebli, J.M.F (Author), Chebli, L.A (Author), da Rocha, J.J.R (Author), da Silva, B.L.P.S (Author), Damião, A.O.M.C (Author), de Azevedo, M.F.C (Author), Féres, O. (Author), Flores, C. (Author), Gasparetti Junior, N.L.T (Author), Lubini, M. (Author), Parra, R.S (Author), Queiroz, N.S.F (Author), Steinwurz, F. (Author), Vilela, E.G (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2022
Subjects:
Biological therapy
Crohn’s disease
Inflammatory bowel disease
Ustekinumab
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