A novel automated image analysis pipeline for quantifying morphological changes to the endoplasmic reticulum in cultured human cells

Background: In mammalian cells the endoplasmic reticulum (ER) comprises a highly complex reticular morphology that is spread throughout the cytoplasm. This organelle is of particular interest to biologists, as its dysfunction is associated with numerous diseases, which often manifest themselves as c...

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Bibliographic Details
Main Authors: Garcia-Pardo, M.E (Author), O’Sullivan, N.C (Author), Simpson, J.C (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2021
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Online Access:View Fulltext in Publisher

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