Modern simulation utilities for genetic analysis

Modern simulation utilities for genetic analysis

Background: Statistical geneticists employ simulation to estimate the power of proposed studies, test new analysis tools, and evaluate properties of causal models. Although there are existing trait simulators, there is ample room for modernization. For example, most phenotype simulators are limited...

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Bibliographic Details
Main Authors: German, C.A (Author), Ji, S.S (Author), Lange, K. (Author), Sinsheimer, J.S (Author), Sobel, E.M (Author), Zhou, H. (Author), Zhou, J. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2021
Subjects:
adult
aged
Aged
article
calculation
Cloud based computing
cloud computing
Cloud Computing
Computational efficiency
computer language
computer simulation
Computer Simulation
Efficiency
Generalized linear mixed models
Generalized linear model
genetic analysis
Genetic architecture
genetic model
Genetic programming
genetic screening
Genetic Testing
geneticist
human
Humans
Integrated simulations
memory
Open source software
pedigree
Pedigree
phenotype
Phenotype
pipeline
Pipelines
Power
Realistic genetic models
Reproducible research
Scientific programming
simulation
Statistical genetics
Step-by-step instructions
Trait simulation
velocity
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