DeltaNeTS+: elucidating the mechanism of drugs and diseases using gene expression and transcriptional regulatory networks

Background: Knowledge on the molecular targets of diseases and drugs is crucial for elucidating disease pathogenesis and mechanism of action of drugs, and for driving drug discovery and treatment formulation. In this regard, high-throughput gene transcriptional profiling has become a leading technol...

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Bibliographic Details
Main Authors:	Chrysinas, P. (Author), Gunawan, R. (Author), Hua, Z. (Author), Noh, H. (Author), Shoemaker, J.E (Author)
Format:	Article
Language:	English
Published:	BioMed Central Ltd 2021
Subjects:	algorithm Algorithms animal Animals biology Cell culture Complex networks Computational Biology Differential gene expressions drug Drug discovery Dynamics Gene expression Gene expression profiles gene expression profiling Gene Expression Profiling gene regulatory network Gene regulatory network Gene regulatory network model Gene regulatory networks Gene Regulatory Networks Gene targets Genetic engineering human Humans Influenza A virus (H1N1) Influenza A virus (H5N1) Influenza A Virus, H1N1 Subtype Influenza A Virus, H5N1 Subtype Mechanism of action Pharmaceutical Preparations procedures T-cells Time-course gene expression profiles Transcription Transcriptional networks Transcriptional profiling Transcriptional regulatory networks
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View Fulltext in Publisher

DeltaNeTS+: elucidating the mechanism of drugs and diseases using gene expression and transcriptional regulatory networks

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