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03001nam a2200697Ia 4500 |
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10.1177-1556264618804962 |
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220706s2018 CNT 000 0 und d |
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|a 15562646 (ISSN)
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| 245 |
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|a Healthy Volunteers’ Perceptions of the Benefits of Their Participation in Phase I Clinical Trials
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| 260 |
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|b SAGE Publications Inc.
|c 2018
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| 856 |
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|z View Fulltext in Publisher
|u https://doi.org/10.1177/1556264618804962
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|a Other than the financial motivations for enrolling in Phase I trials, research on how healthy volunteers perceive the benefits of their trial participation is scant. Using qualitative interviews conducted with 178 U.S. healthy volunteers enrolled in Phase I trials, we investigated how participants described the benefits of their study involvement, including, but not limited to, the financial compensation, and we analyzed how these perceptions varied based on participants’ sociodemographic characteristics and clinical trial history. We found that participants detailed economic, societal, and noneconomic personal benefits. We also found differences in participants’ perceived benefits based on gender, age, ethnicity, educational attainment, employment status, and number of clinical trials completed. Our study indicates that many healthy volunteers believe they gain more than just the financial compensation when they accept the risks of Phase I participation. © The Author(s) 2018.
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|a adolescent
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|a Adolescent
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|a adult
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|a Adult
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|a attitude
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|a Attitude
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|a benefit perception
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|a Biomedical Research
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|a Clinical Trials, Phase I as Topic
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|a decision making
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|a Decision Making
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|a demographic differences
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|a economic motivation
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|a female
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|a Female
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|a healthy volunteers
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|a Healthy Volunteers
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|a human
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|a Humans
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|a male
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|a Male
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|a medical research
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|a middle aged
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|a Middle Aged
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|a motivation
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|a Motivation
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|a normal human
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|a patient selection
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|a Patient Selection
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|a phase 1 clinical trial (topic)
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|a phase I clinical trial
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|a qualitative research
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|a Qualitative Research
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|a remuneration
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|a Remuneration
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|a serial participation
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|a Socioeconomic Factors
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|a socioeconomics
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|a United States
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|a young adult
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|a Young Adult
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| 700 |
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|a Cottingham, M.D.
|e author
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|a Fisher, J.A.
|e author
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|a Kalbaugh, J.M.
|e author
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|a McManus, L.
|e author
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|a Monahan, T.
|e author
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|a Walker, R.L.
|e author
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|a Wood, M.M.
|e author
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| 773 |
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|t Journal of Empirical Research on Human Research Ethics
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