Clinical characteristics of colonoscopy in 448 patients in the Zanzibar Archipelago: a cross-sectional study

Introduction: the aim was to investigate the demographic characteristics, primary colonoscopy findings, main indications, and feature of colorectal cancer (CRC) patients at Mnazi Mmoja Referral Hospital in the Zanzibar Archipelago, Tanzania. Methods: between December 2013 and October 2021, a total o...

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Bibliographic Details
Main Authors: Gubi, M.M (Author), Qu, L.-S (Author)
Format: Article
Language:English
Published: African Field Epidemiology Network 2022
Subjects:
Online Access:View Fulltext in Publisher
LEADER 02325nam a2200193Ia 4500
001 10.11604-pamj.2022.41.310.34185
008 220630s2022 CNT 000 0 und d
020 |a 19378688 (ISSN) 
245 1 0 |a Clinical characteristics of colonoscopy in 448 patients in the Zanzibar Archipelago: a cross-sectional study 
260 0 |b African Field Epidemiology Network  |c 2022 
520 3 |a Introduction: the aim was to investigate the demographic characteristics, primary colonoscopy findings, main indications, and feature of colorectal cancer (CRC) patients at Mnazi Mmoja Referral Hospital in the Zanzibar Archipelago, Tanzania. Methods: between December 2013 and October 2021, a total of 448 eligible participants were finally enrolled in present cross-sectional study. Demographic information and primary colonoscopy findings of each participant were retrieved. Results: among all enrolled subjects, 205 (45.80%) are females, remaining 243 (54.20%) are males. The median age of present cross-sectional study was 47 years old (ranging from 8 to 90 years). The main presenting indications included diarrhea (22.54%), abdominal pain (21.21%), hematochezia (18.53%), difficult defecation (16.96%), mucoid stool (10.49%), and anemia (8.70%). The common identified colonoscopy findings comprised colitis (28.57%), colonic polyps (25.22%), CRC (17.63%), inflammatory bowel disease (IBD) (13.52%), hemorrhoids (4.24%), and colonic diverticulum (4.02%), respectively. Unconditional logistic regression analyses demonstrated the elder group had significant higher risk of CRC (OR, 1.03; 95% CI, 1.01-1.03, P< 0.001), meanwhile a significant higher possibility of suffering hematochezia (OR, 2.29; 95% CI, 1.32-3.99, P=0.003) and anemia (OR, 2.96; 95% CI, 1.46-6.00, p= 0.003) in CRC group. Conclusion: the present study demonstrated that colitis, colonic polyps, CRC, and IBD are the most common colonoscopy diagnoses in Zanzibar. The indication of hematochezia or anemia showed a statistically higher risk of CRC. © Li-Shuai Qu et al. 
650 0 4 |a Colonoscopy 
650 0 4 |a colorectal cancer 
650 0 4 |a cross-sectional study 
650 0 4 |a Zanzibar 
700 1 0 |a Gubi, M.M.  |e author 
700 1 0 |a Qu, L.-S.  |e author 
773 |t Pan African Medical Journal 
856 |z View Fulltext in Publisher  |u https://doi.org/10.11604/pamj.2022.41.310.34185