Gene Amplification of CYP51B: a New Mechanism of Resistance to Azole Compounds in Trichophyton indotineae

Gene Amplification of CYP51B: a New Mechanism of Resistance to Azole Compounds in Trichophyton indotineae

Trichophyton indotineae causes dermatophytosis that is resistant to terbinafine and azole compounds. The aim of this study was to determine the mechanisms of resistance to itraconazole (ITC) and voriconazole (VRC) in strains of T. indotineae. Two azole-sensitive strains (ITC MIC < 0.125 μg/mL; VR...

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Bibliographic Details
Main Authors:	Alshahni, M.M (Author), Feuermann, M. (Author), Guenova, E. (Author), Maeda, M. (Author), Monod, M. (Author), Salamin, K. (Author), Yaguchi, T. (Author), Yamada, T. (Author)
Format:	Article
Language:	English
Published:	NLM (Medline) 2022
Subjects:	ABC transporters CYP51B dermatophytes itraconazole resistance Trichophyton indotineae Trichophyton mentagrophytes type VIII voriconazole
Online Access:	View Fulltext in Publisher

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